August 22, 2005

Dear Shareholder,

Many of you may have read the USATODAY news article (8-16-2005 http://www.usatoday.com/news/nation/2005-08-16-dna_x.htm?POE=click-refer) published August 16, 2005 concerning the successful application of DNAPrint's forensic technology to a criminal investigation surrounding the unidentified, decapitated body of a three year old girl found in Kansas City, Missouri. Based on the evidence analyzed by DNAPrint, authorities now believe the victim, dubbed "Precious Doe," was beaten to death by her parents. This tragic case offers compelling and tangible support to DNAPrint's ongoing efforts in the field of forensic DNA research and technology is DNA evidence of the type analyzed successfully in the Precious Doe case is relatively new. But it is clear to DNAPrint and too many of our customers and supporters, that this technology offers a valuable tool to criminal investigators and law enforcement. DNAPrint has assisted criminal investigations in other notable cases listed below. If you like, you may, do a "google' search for them on the Internet and learn more about them. Additionally, our DNAWITNESS™ web site will be up and running soon. This site will also discuss ongoing criminal cases, news and media links relevant to our forensic products and technology.

We hope that high profile news coverage of cases like "Precious Doe" encourage more detectives, forensic scientists and medical examiners to utilize the benefits offered by our DNAWitness technology. We are constantly seeking ways to expand the market and educate potential consumers for our products. But federal funding for this type of service is sorely lacking and the technology is still relatively new. We appreciate the courage and persistence of our customers and look forward to assisting other criminal investigations in the future

The DNAWITNESS™ product suite now includes:

DNAWITNESS 2.5 -- Assists detectives, forensic scientists and medical examiners in constructing a physical portrait from crime scene DNA, which can be used to corroborate eyewitness reports and/or provide direction for a criminal investigation. DNAWITNESS 2.5 provides a BioGeographical Ancestry report that includes a photo database for reference samples of individuals. Reported ancestral origins are Sub-Saharan African, Native American, East Asian and Indo-European.

EUROWITNESS™ 1.0 -- Tests crime scene DNA to determine more specific geographic origins if the test sample ancestry is 50% or more Indo-European. In some cases this may enable a more specific physical portrait for the DNA donor. EUROWITNESS 1.0 provides a BioGeographical Ancestry report that includes relative percentages of Northwest European, Southeastern European, Middle Eastern or South Asian.

RETINOMES™ -- A predictive test for individual eye color from DNA. Retinome predicts eye color if the sample is 50% or greater European ancestry. Prediction classes include blue, mostly blue, brown or mostly brown. Representative materials from an eye photo database that match the sample are provided for visual reference.

STR-Witness™ -- A genetic "matching" used as a bar code to track and report the samples. STR is the same test used for determining an individual's identity of an available DNA sample. Crime labs run this test to screen the Federal Bureau of Investigation's Combined DNA Index System (CODIS) database for possible matches.

DNAWitness-Y -- A new Y-chromosome test that determines the direct paternal ancestral lineage from the male sex chromosome. DNAWitness-Y can be used as an identification tool in cases where a mixture of male and female samples exists.

The following is a short list of cases that we have been involved with. A few are more notorious than others and for some have resulted in a very large press following for DNAPrint. We would like to see more of that coverage as the public, the police, the detectives, medical examiners and forensic scientists need to be informed that DNAWITNESS™ exists, and it can help them solve their cases.

Louisiana Serial Killer-The Louisiana Serial Killer case came to our attention after a presentation to the forensic community in late 2002. Nearly 2,200 Caucasian males had been screened in Louisiana, based mostly on eyewitness reports that cited a "white male in a white pickup truck" spotted near the scene of two murders. A woman had also reported breaking away from a "white male in a white truck" who tried to accost her. Our report to the task force concluded that the DNA sample came from a person who was 85% sub-Saharan African and 15% Native American, clearly not a Caucasian male. Within six weeks of our report, a DNA sample was obtained from an individual was matched with the crime scene DNA. The suspect promptly fled but was later apprehended in Atlanta, Ga., and extradited to Baton Rouge. The man, Derrick Todd Lee, has since been convicted for two counts of murder. He remains a suspect in at least six other cases.

Boulder, Colorado Case- A young woman left her boyfriend's home after an argument. She was found the next day beaten to death and raped. Despite DNA screening of a significant number of potential suspects, there were no matches and the investigation went cold. The crime scene DNA was loaded into the CODIS database system and in 10+ years there have been no additional hits. Upon analyzing the DNA that was sent to us, we concluded that the genetic ancestry of the sample donor was a mixture of Native American, East Asian and Caucasian, and that from our patent-pending database matching method, these results indicated that this individual was not from the Caucasian community. Up until this time, only white males were considered as possible suspects. The investigation has been re-opened as a result of our findings.

Concord, Calif. Case- A working mother never returned from a walk in the park on her lunch break. Her body was discovered later beaten to death and raped. Asian and Hispanic gangs reportedly had been operating in the park and according to several eyewitness reports members were seen in the vicinity of the crime. Crime scene evidence analyzed by DNAPrint, however, revealed that the suspect was 95% Indo-European or Caucasian. Based on the DNAPrint testing results, the investigation's focus shifted to a small number of Caucasian individuals who were in the park and had been interviewed previously by police. One of these suspects immediately fled the area after providing a DNA sample. He was later apprehended in another state and has now been charged with rape and murder.

Mammoth Lakes Case- In May 2003 the remains of a body were unearthed in a shallow grave near the resort town of Mammoth Lakes, California. The remains were sent to the San Francisco Medical Examiner's office, which determined that the victim was a woman, 30 to 40 years old, of Southeast Asian ancestry. The medical examiner's findings were corroborated by eyewitness reports of a short possibly Asian woman in the area complaining about an abusive spouse or significant other. In August 2004, however, investigators shifted the focus of their investigation after a DNA sample sent to DNAPrint for analysis determined that the victim was 100% Native American.

The Minstead Case -- We were contacted by Scotland Yard and the London Metropolitan Police to evaluate a DNA sample obtained from an individual believed to be responsible for nearly 90 incidents of reported breaking and entering, theft, assault and rape of elderly women in London. We were asked to determine, if possible, the suspect's ancestry. Based on the fact his sample contained a minor component of Native American ancestry, we believed he was from the Caribbean Islands and not from continental Africa. The pool of potential African male suspects in London between the ages of 30 and 45 number in the 50,000+ range. To build this case, we needed a larger number of reference samples from the Caribbean Scotland Yard and the Metropolitan Police sent a representative to the Caribbean to collect volunteer samples from the Caribbean police and forensic workers. Through the application of our forensic technology, we narrowed the suspect pool significantly from 50,000+ to around 500 to 1,000 individuals.

You may also have noted our efforts with Penn State University, including the use of a 3-D imaging camera. We will be scanning the photos and searching for additional genetic markers. We hope that some day not too distant, DNAWITNESS will include a 3-D imaging capability that is reconstructed from a composite of DNAWITNESS photo database samples and DNA markers, creating a 'fuzzy photograph' for detectives in 3-dDimaging.

The benefits we derive from the forensics market has a direct application to our research and product development in the pharmacogenomics market If we are able to discern a person's eye color, hair color or bone density from a DNA sample and we are able to link it to other descriptive or phenotypic markers, then we have a much better chance at predicting whether or not a patient will or will not respond to a particular drug or treatment. In effect, forensics is our training ground.

Thank you for your support.,

Company Contact:
Richard Gabriel
CEO and President
941 366-3400
-or-
Ron Stabiner
The Wall Street Group, Inc.
212-888-4848